Happy Holidays from the Kick Knowledge crew! In this episode, Zach and Steven are once again joined by friends Frank Stevens and Gino Van Oostrom, and determine the end of the year bracket for our favorite album of 2017!
#11: A Very Kick Knowledge Christmas Pt. 2 (w/ Frank and Gino)
muscle pills to get ripped
References:
git.nusaerp.com
Ipamorelin, Sermorelin, and Tesamorelin are three peptides that
have become popular in the field of anti-aging medicine, hormone replacement therapy,
and sports performance enhancement. Each peptide has its own unique mechanism of action, dosing schedule, therapeutic indications,
and side-effect profile. Understanding these differences is essential for clinicians who wish to prescribe them responsibly,
as well as for patients seeking a clear picture of what each treatment offers.
Ipamorelin vs Sermorelin: Which Peptide Therapy Is Right?
Mechanism of Action
Ipamorelin is a selective growth hormone secretagogue that stimulates the pituitary gland to release growth hormone (GH) by binding to ghrelin receptors.
Unlike some other GH-secretagogues, ipamorelin has minimal influence on prolactin or cortisol levels,
which reduces the likelihood of unwanted endocrine side
effects.
Sermorelin is a synthetic analogue of growth hormone-releasing hormone
(GHRH). It mimics the natural pulse of GHRH and triggers
the release of GH in a more physiologic manner.
Sermorelin’s action is generally slower and less potent than that of ghrelin agonists,
but it tends to preserve normal feedback mechanisms.
Dosing and Administration
Ipamorelin is typically administered via subcutaneous
injection at doses ranging from 200 to 400 micrograms
per day, split into multiple injections. The peptide is stable for several weeks when stored properly, allowing patients to self-inject on a daily basis or
in a cyclical regimen (e.g., 2–3 days on followed by 1–2 days off).
Sermorelin dosing usually falls between 100 and 250 micrograms per day,
injected once daily. The injection is often taken at night
because GH secretion naturally peaks during sleep.
Sermorelin’s shorter half-life necessitates more frequent
injections if higher levels of GH are desired.
Therapeutic Indications
Ipamorelin is frequently used for:
Enhancing lean muscle mass in elderly patients.
Improving skin elasticity and reducing fine lines.
Supporting recovery after surgery or injury.
Managing cachexia in chronic disease states.
Sermorelin is often prescribed for:
Growth hormone deficiency (GHD) diagnosed via stimulation tests.
Idiopathic short stature in children, when used under pediatric
guidance.
Anti-aging protocols that require a more physiologic GH release pattern.
Side Effect Profile
Because ipamorelin’s activity is highly selective, the most common side effects include mild injection site reactions,
temporary headaches, and occasional water retention. Rarely, patients
may experience fatigue or dizziness.
Sermorelin can cause similar local injection reactions but has a higher likelihood of
inducing transient increases in prolactin levels,
which may lead to breast tenderness or lactation in rare cases.
There is also a theoretical risk that chronic use could blunt the body’s natural GH axis if not monitored properly.
Cost and Accessibility
Ipamorelin tends to be more expensive per dose due to its
synthetic complexity and higher potency. Sermorelin, while
still costly compared to generic peptides, can be slightly cheaper because it
requires lower doses for comparable therapeutic effects.
Both peptides are typically prescribed by specialists in endocrinology or regenerative medicine and may not be covered by insurance unless
a specific medical diagnosis is documented.
Choosing the Right Therapy
Patients seeking rapid muscle gain or postoperative recovery:
Ipamorelin’s stronger GH stimulus makes it the preferred choice.
Individuals with confirmed growth hormone deficiency: Sermorelin offers a
more physiologic stimulation and aligns closely with standard diagnostic protocols.
Those concerned about prolactin elevation: Ipamorelin’s minimal impact
on prolactin is advantageous.
Budget constraints: Sermorelin may be slightly more affordable, but
cost varies by supplier.
In practice, the decision should involve a thorough endocrine evaluation, consideration of patient goals,
and close monitoring of serum GH and IGF-1 levels to avoid over-stimulation or suppression of the hypothalamic–pituitary
axis.
Nationwide Prescription hCG, Wegovy (Semaglutide), and
Vitamin B12 Shots
hCG (Human Chorionic Gonadotropin)
hCG is a glycoprotein hormone that can mimic luteinizing hormone (LH)
activity. In the context of peptide therapy, it is often prescribed
for:
Supporting testosterone production in men with hypogonadism.
Assisting in fertility treatments by stimulating ovarian function in women or Leydig cell activity in men.
Prescription hCG is available nationwide through specialty pharmacies and endocrinology practices.
Patients typically receive subcutaneous injections ranging from 1500 to 5000 IU per week, depending on the therapeutic goal.
Because hCG can influence estrogen levels, careful monitoring of hormone panels is essential.
Wegovy (Semaglutide)
Wegovy is a once-weekly injectable glucagon-like peptide-1
(GLP-1) receptor agonist approved for chronic weight management in adults with obesity or overweight and at
least one weight-related comorbidity. The drug delivers 2.4 mg per week, gradually titrated to reduce gastrointestinal side
effects.
Nationwide access to Wegovy is facilitated through prescription coverage by
many insurance plans, though out-of-pocket costs can still be significant.
It has been shown to produce an average weight loss of
15–20% over 68 weeks in clinical trials and also improves glycemic control, blood pressure,
and lipid profiles.
Vitamin B12 Shots
Vitamin B12 injections (usually methylcobalamin or cyanocobalamin) are routinely prescribed for patients with deficiency,
pernicious anemia, malabsorption syndromes, or those on strict vegan diets.
Intramuscular doses range from 1000 to 2000 micrograms weekly for several weeks,
then tapering to monthly maintenance.
Nationwide distribution of B12 shots is straightforward, as most
primary care practices and pharmacies can administer them.
They are inexpensive relative to other peptide therapies but carry minimal risk; the
primary concern is a potential allergic reaction at
the injection site.
Integration in Clinical Practice
Patients often combine hCG with testosterone replacement
or ipamorelin for anabolic benefits while using Wegovy to
manage body weight concurrently. Vitamin B12 can be added to support overall metabolic health
and mitigate fatigue associated with other peptide therapies.
A multidisciplinary approach—combining endocrinology,
nutrition, and lifestyle counseling—is recommended for optimal
outcomes.
Toggle Menu
A toggle menu is a user interface element that allows patients or clinicians to quickly access different sections of a treatment plan or patient portal.
In the context of peptide therapy management,
a well-designed toggle menu might include:
Peptide Overview: Quick links to ipamorelin, sermorelin, and
tesamorelin profiles.
Prescription Tracker: View current prescriptions for hCG, Wegovy,
B12, and any other medications.
Lab dianabol results before and after pics:
Download or view recent hormone panels (GH, IGF-1, testosterone, prolactin).
Side Effect Log: Record and monitor adverse events after each injection.
Appointment Scheduler: Book follow-up visits
with endocrinologists or nutritionists.
Educational Resources: Access patient guides,
FAQs, and research articles.
Implementing such a toggle menu in an electronic health record or patient portal
can streamline communication, reduce administrative burden, and
enhance adherence to complex peptide regimens. It also empowers patients by
giving them real-time access to their treatment data
and educational materials, thereby fostering engagement and informed decision-making.
Additional, natural recovery assumes no extreme harm was accomplished to the Hypothalamic-Pituitary-Testicular-Axis
(HPTA) by way of improper anabolic steroid use. As a final notice, ladies have
no must complement with exogenous testosterone when using Oral Turinabol.
Turinabol, a spinoff of Dianabol, is an anabolic steroid known for its distinctive capacity to supply regular muscle features and energy
enhancements with minimal water retention. It’s favored for its balanced anabolic and androgenic results,
making it a preferred selection for athletes looking for efficiency enhancement with out extreme bulk.
Nonetheless, it carries dangers like liver injury and cardiovascular points, requiring cautious use.
Dianabol, a potent anabolic steroid, dramatically boosts muscle mass and strength.
This is not to be confused with Oxandrolone, which is otherwise known as Anavar.
Almost instantly after, the pharmaceutical company
Syntex sold Oxymetholone underneath the name Anadrol-50 whereas Parke Davis & Co.
additionally manufactured it, although they did so underneath the Androyd commerce name.
After its preliminary launch onto prescription markets, Anadrol was rapidly prescribed and used for
a mess of medical situations ranging from geriatric
atrophy to combating infections. It’s most famous and well-liked use as a medication, nevertheless, was
within the remedy of anemia. Anadrol was prescribed here to extend the pink blood cell count and hemoglobin levels of the anemic particular person.
This course of entails the protein-building mechanism of cells
– in other words, the basic constructing blocks of lean muscle tissue make it
apparent why this is such a desirable impact for steroid-using bodybuilders.
With a higher-than-normal price of protein synthesis occurring, your muscular tissues can grow faster
and more extensively – it sounds simple, but that’s the last word goal
of using steroids (at least for bulking). Primobolan can help
you achieve that hardened, ripped look with no water retention. Preserving muscle
tissue is a critical good thing about Primobolan, as it stops you from changing into catabolic
while your chopping diet is a calorie deficiency.
Primobolan increases energy, recovery, and muscle endurance
so that it will contribute positively to your
exercises. Small doses and short cycles are important
for utilizing Halotestin safely. Even 10mg every day of this oral steroid will present very noticeable benefits.
Steroid use suppresses the body’s production of testosterone,
and when the cycle ends, the body might wrestle to renew regular testosterone manufacturing.
PCT aims to stimulate the testes to begin out producing
testosterone again, preventing muscle loss and minimizing the
unwanted facet effects of low testosterone, corresponding
to fatigue, melancholy, and decreased libido. The perceived need for oral steroids stems from a posh interaction of things, primarily driven by
the will to boost physical performance and look.
Individuals involved in competitive sports activities, bodybuilding,
and health usually seek these substances to speed up muscle Growth Factor Plus vs. Hormonal Treatments, improve power, cut back physique fat,
and improve recovery instances. This desire can be notably intense in environments where bodily prowess
is highly valued or directly linked to career development and
financial success.
It also binds to SHBG (sex hormone-binding globulin) with a excessive
affinity, rising free testosterone levels. When a user’s estrogen-testosterone ratio becomes unbalanced and estrogen levels rise excessively in males, we see increases in visceral fats (35).
Firstly, Dianabol causes noticeable water retention as a result
of aromatization.
Methenolone is a DHT-derived steroid available in both oral and injectable varieties, with
the injectable generally known as Primobolan Depot. The injectable version is considered far more highly effective than the oral type and, as such, is more in style amongst bodybuilders and performance athletes.
The most useful effects of Primobolan embody its capability to spice up nitrogen retention and hold
the physique in an anabolic state. Suppose of anabolic steroids, and the name Dianabol (Dbol)
is commonly the primary to come back to your mind.
It’s long been the most popular and revered steroid, and for good cause.
This PCT plan helps reignite testosterone, fight cortisol, steadiness estrogen, and
help organ recovery. Oral-only cycles nonetheless require proper PCT to bridge
your physique back to baseline. Increased power, endurance,
and work capacity permit for longer, more intense coaching periods.
This leads to better restoration and overall improvements in athletic output.
The SteroidsLive weblog covers the newest information in bodybuilding, health, sports activities, well being and diet.
We attempt to provide our readers — athletes, fitness and sports buffs, and people
excited about all-around well being — the most recent news,
info, and of course — the gossip. You should always go along with a milk thistle supplement before,
during, and after a steroid cycle.
A pure hormone precursor that helps testosterone production, vitality, and adrenal balance—crucial
after a suppressive cycle. Muscle development, or hypertrophy, occurs when protein synthesis exceeds protein breakdown—especially after resistance training
causes micro-damage to muscle fibers. The body repairs this injury, rebuilding the muscle
stronger and thicker. Prescription guidelines for Anadrol various a
great deal all through the 1950s – 1980s and was depending on the
medical situation handled, in addition to continually changing FDA pointers.
Medical Anadrol dosages ranged from 2.5mg taken 3 times per day
all the finest way up to 30mg per day. Finally within the Nineteen Seventies,
the FDA issued a tenet of 1 – 2mg per kg of bodyweight per day.
Some bodybuilders will even use this drug as a type
of on-cycle and post-cycle remedy as it’s an excellent anti-estrogen drug.
Oral steroids, also referred to as anabolic-androgenic steroids
(AAS), are synthetic variations of the male hormone
testosterone. They work by binding to androgen receptors
inside cells, influencing DNA transcription and protein synthesis.
This results in elevated muscle mass (anabolism),
enhanced energy, and lowered recovery time.
Understanding esters in organic chemistry can be difficult
for the non-scientist. Nonetheless, you’ll quickly come across a quantity of totally different esters of testosterone on the planet of steroids, and
for sure, you will want to know what all of it means.
When it comes to the most effective location for your steroid injections – as a
newbie, it’s usually recommended to begin at one of the
largest muscle tissue – the buttock space.
What most people don’t realise is plenty of nations throughout the world allow the personal use of anabolic steroids.
The reason many people think the un-prescribed use of anabolic steroids is towards the law is simply due to the dangerous media protection anabolic steroids get in the Usa.
You’re positively not going to get the huge array of anabolic
steroids from your GP that you want and want for bodybuilding or powerlifting functions.
Nevertheless, Winstrol is outstanding in different areas,
significantly enhancing performance and cutting and weight-reduction plan, the place the primary
goal is to attain a very lean, dry, exhausting, and outlined physique.
At doses anywhere above the female really helpful range of 5-10mg/day, virilization is undoubtedly a risk.
Some women may be sensitive enough at those low doses to experience negative effects, but as long as you scale
back the dose or stop utilizing Anavar, they want to go away alone.
If you’re not too concerned about testosterone,
you need to use Testosterone Cypionate (a slow-acting ester), offering energy and measurement gains and a few fat loss.
However, lifting weights is commonly the main explanation for lower back ache skilled by many
bodybuilders. While understanding the intricacies of steroid packaging is a big step in figuring out illicit or inferior merchandise, it is equally necessary to have the ability to acknowledge legitimate on-line sources
of steroids. Hence, it is essential to know these dangers earlier than venturing into online
steroid purchases. The legal landscape concerning steroids varies significantly throughout the globe, making
it crucial to know the worldwide laws and rules.
Key international locations have distinct insurance policies
and enforcement practices regarding the use, possession, and sale of those substances.
This part will study and compare the steroid laws of these major jurisdictions, highlighting
the complexities and intricacies of the worldwide legal
framework. Yes, but it’s essential to begin with delicate compounds like Anavar or low doses of Testosterone.
‘HGH gut’ is often noticed in IFBB bodybuilders, which
could be attributed to the enlargement of internal organs such as the intestines
and liver (9). Nonetheless, in terms of pure muscle acquire, we rank trenbolone among the
best bulking steroids. In our experience, using Decaduro alone is not going to yield significant muscle
positive aspects. Thus, for max muscle hypertrophy, stack Decaduro
with D-Bal, Anadrole, Trenorol, and/or Testo-Max.
What accompanied this was additionally an increase in counterfeiting operations to
find a way to benefit from the authorized situation and media publicity,
which was causing high demand. Bodybuilding lovers and athletes typically use anabolic steroids to boost their efficiency and achieve their fitness objectives.
While buying steroids on-line could be convenient and cost-effective,
it can be dangerous. The web has quite a few web sites claiming
to promote real steroids, but not all are reliable.
Subsequently, discovering a dependable source that
offers high-quality steroids at an inexpensive value is essential.
Steroid cycles are rigorously planned periods of anabolic steroid use,
followed by off-periods, designed to help customers obtain specific health
goals such as muscle progress, power enhance, or fats loss.
These cycles can differ significantly in size, dosage, and
the types of compounds used, relying on the individual’s experience degree, objectives, and bodily situation.
We provide a extensive range of premium, lab-tested anabolic steroids that will assist you obtain your health and physique goals faster and extra successfully.
Whether Or Not you’re a seasoned athlete or just starting your journey,
we’re right here to information you each step of the means in which.
As compared to the price usually paid on the black market,
unfortunately you will pay a great bit extra for prescription steroids.
It is a tradeoff however before you let it bother you think about it for a minute.
More importantly and it’s already been stated however is
price repeating, you might be throughout the line of the law and that is price more than you can attainable know.
Some of it is feasible for you to to cowl a few of the price via your insurance coverage and nearly at all times age will play a
large function in this issue.
Fertility may be impaired on account of the suppressive effects of AAS on gonadotropin manufacturing,
causing disruption of the menstrual cycle. In addition, AAS have virilizing
results, which clearly is not an issue in men however has great scientific
significance in women. These results include dysphonia or
deepening of the voice, hirsutism and clitoromegaly.
Sure, authorized steroids present in respected online shops are typically secure to make use of as they are
produced from pure elements. Nevertheless, it’s essential to follow the beneficial dosage
and consult a healthcare professional before beginning any complement routine.
Lastly, before you buy anabolic steroids on-line from
a legal supplier.
References:
PedsElite